Inclunox® and Inclunox® HP (Enoxaparin sodium solution for injection 100 mg/mL and 150 mg/mL (High Potency)) are biosimilars of reference biologic drugs LOVENOX* and LOVENOX* HP.
Indications have been granted on the basis of similarity between Inclunox® and Inclunox® HP and the reference biologic drugs LOVENOX* and LOVENOX* HP.
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PrINCLUNOX® (enoxaparin) is indicated for:
The prophylaxis of thromboembolic disorders (deep vein thrombosis) in patients undergoing:
o orthopedic surgery of the hip or knee. In addition, Inclunox® is indicated in hospital or after hospital discharge for long-term prevention of venous thromboembolic diseases following hip replacement surgery. o high risk abdominal, gynecological, or urological surgeries; o colorectal surgery.
The prophylaxis of deep vein thrombosis (DVT) in medical patients who are at moderate risk of DVT and who are bedridden due to moderate to severe acute cardiac insufficiency (NYHA Class III or IV heart failure), acute respiratory failure revealing or complicating chronic respiratory insufficiency not requiring ventilatory support and acute respiratory infections (excluding septic shock), who require short-term prophylaxis of deep vein thrombosis.
The prevention of thrombus formation in the extra-corporeal circulation during hemodialysis.
PrINCLUNOX® (enoxaparin) is also indicated for:
The treatment of deep vein thrombosis, with or without pulmonary embolism.
The treatment of unstable angina or non-Q-wave myocardial infarction, concurrently with ASA.
Treatment of acute ST-segment Elevation Myocardial Infarction (STEMI), including patients to be managed medically or with subsequent Percutaneous Coronary Intervention (PCI).
Inclunox® and Inclunox® HP are the sixth Sandoz biosimilars available in Canada.
Click here to consult the product monograph of Inclunox® and Inclunox® HP
® Registered trademark owned or used under license by Sandoz Canada Inc.
* Registered trademark owned by its respective registrant